Brock of the 49ers Purdy with an injury to the toe; Mac Jones to start against Rams

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A short week was not nice for the 49ers of San Francisco, and the team will be without key offensive pieces, including the quarter-Arrière Brock Purdy, against the Rams of Los Angeles on “Thursday Night Football”.

Large receivers Ricky Pearsall and Jauan Jennings will not be available for 49ers on Thursday evening.

Purdy missed weeks 2 and 3 after having undergone an injury to the toes at the opening of the season, but returned during the week 4 against the Jacksonville jaguars. During the defeat of 26-21, the injury of the toes of Purdy exploded again.

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The quarter of the 49ers of San Francisco, Brock Purdy, takes place to pass against the Bears in Chicago during the first half in Santa Clara, California, on December 8, 2024. (Photo Eakin Howard / AP)

Mac Jones will make his third start of the season.

He replaced Purdy in previous matches, completing 66% of his passes for 563 yards with four affected and interception over this period. The 49ers won these two games.

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Jones is also faced with a knee injury, but the 49ers said he was a participant in the three injury reports this week. He has no game status before Thursday evening.

Jennings fights against the ankle and the rib injuries, while Pearsall was limited by a knee problem. The 49ers will turn to the receivers Kendrick Bourne and Demarcus Robinson, the latter, made his debut of the season last week after having served a suspension.

San Francisco will also be without the receiver Jordan Watkins (calf) and the defensive winger Robert Beal (ankle), while the defensive platform CJ West (Pouce) is questionable.

The quarter of the 49ers of San Francisco, Brock Purdy (13), launched a pass against the Rams of Los Angeles in the second quarter at the Levi’s stadium on December 12, 2024. (Cary Edmondson / Imagn Images)

It is already a pivotal match in the NFC West race, the two teams entering 3-1 in the first of the two games this season. The Rams rebounded last week with a victory after an overwhelming defeat against the Eagles of Philadelphia, when two goals blocked on the ground sealed the defeat.

Matthew Stafford and the Rams offensive prospered, and the addition of Davante Adams to play alongside Puka Nacua and Kyren Williams led to the fourth yards per match in the league this season.

Brock Purdy of the 49ers of San Francisco after a defeat of 26-21 against the Jacksonville jaguars in Levi’s Stadium on September 28, 2025, in Santa Clara, California. (Images Brooke Sutton / Getty)

San Francisco’s head coach Kyle Shanahan will have to rely on Star Ball Christian McCaffrey and Jones’ precision to prevent Rams from moving away.

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