- The report finds that 78% choose OpenAI models, but many are spread across families and generations.
- Anthropic began to resume in mid-2025, with 75% using Sonnet/Opus 4.5
- M365 Copilot is still a favorite, far outpacing Gemini for Workspace
ChatGPT maker OpenAI remains the most popular template vendor chosen by enterprises, according to new data from CIOs of Global 2000 companies, with nearly four in five (78%) choosing OpenAI templates for production.
However, models from rival companies Anthropic and Google are growing in popularity, with increased adoption by Anthropic starting in mid-2025.
But more importantly, data from venture capital giant Andreessen Horowitz (a16z) reveals that specific use cases will play the most important role in the model’s decision.
OpenAI’s popularity soon to be challenged by Anthropic
CIOs prefer OpenAI for general chat, knowledge management, and customer support, but Anthropic is gaining popularity for its better performance in software development and data analysis. CIOs noted that Gemini performed well overall, but lagged in some coding use cases.
And just like hybrid and multicloud models, companies are increasingly moving away from a single provider: 81% of them now use three or more model families at the testing or production stages. This figure has already increased from 68% in less than a year.
As for Anthropic, its new models are clearly proving more popular than the previous generation models. Three out of four Anthropic customers had Sonnet 4.5 or Opus 4.5 in production, compared to OpenAI whose customers still use many earlier models. Less than half (46%) used GPT-5.2.
Part of this trend could be attributed to the models’ reasoning capabilities, with companies claiming faster time to value, slower engineering, and higher confidence.
a16z also highlighted the proliferation of Microsoft 365 Copilot in the enterprise world, much more popular than Google Gemini for Workspace.
Looking ahead, most companies still measure the ROI of AI in terms of productivity and cost reduction, but employee and customer satisfaction and retention are starting to gain traction. Four out of five Global 2000 companies expect to break even or generate a higher return on investment.
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