NEWYou can now listen to PK Press Club articles!
With the 2026 NFL schedule now officially released, sportsbooks wasted no time in releasing the opening lines for Week 1.
Headlined by a Super Bowl rematch Wednesday night between the Seahawks and Patriots, as well as the first-ever NFL game in Australia between the Rams and 49ers, opening week is absolutely jam-packed.
And even though kickoff is still a few months away, it’s never too early to take a look at the Week 1 odds after the schedule is released.
Here are the lines for every Week 1 game on DraftKings Sportsbook starting May 15.
This page may contain affiliate links to legal sports betting partners. If you register or place a bet, FOX Sports may be compensated. Learn more about Sports betting on FOX Sports.
WEDNESDAY September 9
Patriots @ Seahawks
Spread: Seahawks -3.5
Moneyline: Seahawks -205, Patriots +170
O/U: 44.5
THURSDAY September 10
49ers @ Rams (Australia)
Spread: Rams -2.5
Moneyline: Rams -155, 49ers +130
O/U: 48.5
SUNDAY September 13
Saints @ Lions
Spread: Lions -7
Moneyline: Lions -325, Saints +260
O/U: 48.5
Bear @ Panthers
Spread: bear -2.5
Moneyline: Bears -135, Panthers +114
O/U: 44.5
Ravens @ Colts
Spread: Ravens -3.5
Moneyline: Ravens -185, Colts +154
O/U: 49.5
Bills @ Texans
Spread: invoices -1.5
Moneyline: Bills -112, Texans -108
O/U: 45.5
Falcons @ Steelers
Spread: Steelers -3
Moneyline: Steelers -175, Falcons +145
O/U: 42.5
Buccaneers @ Bengals
Spread: Bengals -3.5
Moneyline: Bengals -198, Buccaneers +164
O/U: 50.5
Browns @ Jaguars
Spread: Jaguars -7
Moneyline: Jaguars -285, Browns +230
O/U: 40.5
Jets@Titans
Spread: Titans -3
Moneyline: Titans -170, Jets +142
O/U: 39.5
Commanders @ Eagles
Spread: Eagles -5.5
Moneyline: Eagles -238, Commanders +195
O/U: 46.5
Packers @ Vikings
Spread: Packers -1.5
Moneyline: Packers -125, Vikings +105
O/U: 44.5
Cardinals @ Chargers
Spread: Chargers -11.5
Moneyline: Chargers -625, Cardinals +455
O/U: 45.5
Dolphins @ Raiders
Spread: Raiders -3
Moneyline: Raiders -180, Dolphins +150
O/U: 41.5
Cowboys @ Giants
Spread: Cowboys -2.5
Moneyline: Cowboys -130, Giants +110
O/U: 48.5
MONDAY September 14
Broncos @Chiefs
Spread: Chiefs -2.5
Moneyline: Chiefs -155, Broncos +130
O/U: 42.5
